19. Le NM, Yildirim M, Sugihara H , Wang Y, Jazayeri M, Sur M. Mixture of Learning Strategies Underlies Rodent Behavior in Dynamic Foraging. Biorxiv: Link

​

• Our results revealed a remarkable degree of mixing between different strategies even in expert animals, such that model-free and inference-based

learning modes often co-existed within single sessions. Together, these results invite a re-evaluation of the stationarity of behavior during dynamic

foraging, provide a comprehensive set of tools to characterize the evolution of learning strategies, and form the basis of understanding neural circuits

involved in different modes of behavior within this domain.

​

18. Yildirim M, Delepine C, Feldman D, Pham V, Chou S, Ip JPK, Nott A, Tsai LH, Ming G, So PTC, Sur M. Label-free three-photon imaging of intact human

cerebral organoids: tracking early events in brain development and deficits in Rett Syndrome. Biorxiv: Link

​

• Our label-free imaging system constitutes a particularly useful platform for tracking normal and abnormal development in individual organoids, as well as

for screening therapeutic molecules via intact organoid imaging.

​

​

17. Rikhye R, Yildirim M, Hu M, Breton-Provencher V, Sur M. Reliable sensory processing in mouse visual cortex through inhibitory

interactions between Somatostatin and Parvalbumin interneurons. Journal of Neuroscience; Link

​

• Our results, supported by computational models, suggest that somatostatin interneurons (SST-INs) increase

pyramidal neuron reliability by suppressing parvalbumin interneurons (PV-INs) via the inhibitory SSTPV circuit.

Using a novel movie classification task, we further show that, by reducing variability, activating SST-INs can

improve the ability of mice to discriminate between ambiguous stimuli. Together, these findings reveal a novel

role of the SST-PV circuit in modulating the fidelity of neural coding critical for visual perception.

• Article highlighted in MIT website: Link

• Article highlighted in Picower Institute website: Link

• Article highlighted in NIBIB website: Link

​

​

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16. Zheng C.,, Park JK, Yildirim M., Boivin J.R., Xue Y., Sur M., So P.T.C., Wadduwage D.N. De-scattering with Excitation Patterning enables rapid wide-field

imaging through scattering media. Science Advances (2021); 7(28): eaay5496. Link

• We introduce a novel technique called De-scattering with Excitation Patterning or “DEEP,” which uses patterned nonlinear excitation followed by

• computational imaging–assisted wide-field detection

• Article highlighted in MIT website: Link.

​

​

15. Yildirim M, Hu M, Le NM, Sugihara H, So PTC, Sur M. Quantitative third-harmonic generation imaging of mouse visual cortex areas

reveals correlations between functional maps and structural substrates. Biomedical Optics Express (2020); 11(10): 5650-5673. Link

• Our paper for the first time demonstrates a strong correlation between structural substrates of visual cortical areas, represented

• by EALs, and their functional visual field representation maps

• Article highlighted in NEI website: Link.

• Article highlighted in MIT's website: Link.

​

​

14. Yildirim M, Sugihara H, So PTC, Sur M. Functional imaging of visual cortical layers and subplate in awake

    mice with optimized three-photon microscopy. Nature Communications (2019); 10(1):177.

• Our paper characterizes for the first time evoked neuronal responses in all cortical layers and subplate

    of awake mice as well as safety limits of three-photon microscopy for the sake of cell’s physiology.

• Article highlighted in NIH Director Francis Collins’s blog: Link

• Article highlighted in MIT’s website: Link

• Article highlighted in many scientific magazines such as BioOpticsWorld: Link

​

​

13. Karaayvaz M, Silberman RE, Langenbucher A, Saladi SV, Ross K, Zarcaro E,

 Desmond A, Yildirim M,Vivekanandan V, Ravichandran H, Mylavagnanam R, Specht MC,

 Ramaswamy S, Lawrence M, Amon A, Ellisen LW. Aneuploidy and deregulated DNA

 damage response define haploinsufficiency in breast tissues of BRCA2 mutation carriers.

 Science Advances; Link

• Our paper provides evidence for BRCA2 haploinsufficiency and associated DNA damage in

vivo that precede histologic abnormalities. These results provide unanticipated opportunities

for new cancer risk assessment and prevention strategies in high-risk patients.

​

​

12. Hogan B, Kovalska E, Zhukova M, Yildirim M, Craciun M, Baldycheva A. 2D WS2

Liquid Crystals: Tunable Functionality Enabling Diverse Applications. Nanoscale;

(2019); (31):35-49.

• The first observation of liquid crystalline dispersions of liquid phase-exfoliated tungsten

disulfide flakes is reported in a range of organic solvents. The liquid crystals demonstrate

significant birefringence as observed in the linear and circular dichroism measurements respectively.

In particular, linear dichroism is observed throughout the visible range while broad-band circular

dichroism can be observed in the range from 500–800 nm. Under an applied magnetic field of ±1.5 T

the circular dichroism can be switched ON/OFF, while the wavelength range for switching can be

tuned from large to narrow range by the proper selection of the host solvent. In combination with

photoluminescence capabilities of WS2, this opens a pathway to a wide variety of applications,

such as deposition of highly uniform films over large areas for photovoltaic and terahertz devices.

​

​

​

11. Yildirim M, Okutucu T, Dursunkaya Z. A numerical algorithm to determine straightness error, surface roughness,

  and waviness measured using a fiber optic interferometer. Optics and Laser Technology (2016); 85, 19-29.

 

• In this paper, a novel interference fringe counting technique is developed to convert the intensity of interference data into

displacements in the range of micrometers to millimeters while simultaneously resolving external dynamic effects. This

technique can detect three orders of magnitude different dynamic displacements with sub-micrometer resolution. 

The current methodology can be utilized in different applications which require measuring straightness error of lead-screw

driven stages, large-area surface profile of specimens, and vibration of actuators such as stepper motors.

​

 

 

 

​

​

10. Yildirim M, Quinn K, Kobler J, Zeitels SM, Georgakoudi I, Ben-Yakar A. Quantitative differentiation of normal and

scarred tissues using second-harmonic generation microscopy. Scanning (2016); 38 (6), 684-693.

​

• In the present study, image analysis of both fiber alignment and density from depth‐resolved second‐harmonic generation

images in epi‐detection mode enabled the quantification of the increased collagen fiber deposition and alignment typically

observed in fibrosis. The epi‐detection geometry is the only viable method for in vivo imaging as well as imaging thick turbid

tissues. These quantitative endpoints, clearly differentiating between control and scarred hamster cheek pouches, provide an

objective means to characterize the extent of vocal fold scarring in vivo in preclinical and clinical research. In particular, this

non‐invasive method offers advantages for monitoring scar treatments in live animals and following the effects of

scarring‐related treatments such as application of steroids or drugs targeting pathways involved in fibrosis

​

 

​

 

 

9. Gabay I, Subramanian K, Martin C, Yildirim M, Tuchin V, Ben-Yakar A. Increasing the penetration depth for ultrafast

laser tissue ablation using glycerol based optical clearing. In Dynamics and Fluctuations in Biomedical Photonics XIII

(2016); (Vol. 9707, p. 97070X).

​

• Fresh porcine vocal folds were excised and applied a biocompatible OC agent (75% glycerol). Collimated transmittance

was monitored. The tissue was optically cleared and put under the microscope for ablation threshold measurements at

different depths. The time after which the tissue was optically cleared was roughly two hours. Fitting the threshold

measurements to an exponential decay graph indicated that the scattering length of the tissue increased to 83±16 μm, which

is more than doubling the known scattering length for normal tissue. Optical clearing with Glycerol increases the tissue

scattering length and therefore reduces the energy for ablation and increases the maximal ablation depth. This technique can

potentially improve clinical microsurgery.

​

​

 

 

 

 

8. Yildirim M, Durr N, Ben-Yakar A. Tripling the maximum imaging depth with third-harmonic generation microscopy.

Journal of Biomedical Optics (2015); 20 (9), 096013-096013.

• The growing interest in performing high-resolution, deep-tissue imaging has galvanized the use of longer excitation

wavelengths and three-photon-based techniques in nonlinear imaging modalities. This study presents a threefold

improvement in maximum imaging depth of ex vivo porcine vocal folds using third-harmonic generation (THG) microscopy

at 1552-nm excitation wavelength compared to two-photon microscopy (TPM) at 776-nm excitation wavelength.

The experimental, analytical, and Monte Carlo simulation results reveal that THG improves the maximum imaging depth

observed in TPM significantly from 140 to 420  μm in a highly scattered medium, reaching the expected theoretical imaging

depth of seven extinction lengths. This value almost doubles the previously reported normalized imaging depths of 3.5 to 4.5

extinction lengths using three-photon-based imaging modalities. Since tissue absorption is substantial at the excitation

wavelength of 1552 nm, this study assesses the tissue thermal damage during imaging by obtaining the depth-resolved

temperature distribution through a numerical simulation incorporating an experimentally obtained thermal relaxation time (τ).

By shuttering the laser for a period of 2τ, the numerical algorithm estimates a maximum temperature increase of ∼2°C at the

maximum imaging depth of 420  μm. The paper demonstrates that THG imaging using 1552 nm as an illumination

wavelength with effective thermal management proves to be a powerful deep imaging modality for highly scattering

and absorbing tissues, such as scarred vocal folds

 

​

7. Hoy CL, Ferhanoglu O, Yildirim M, Kim KH, Karajanagi SS, Chan KMC, Kobler J, Zeitels SM, Ben-Yakar A.

Clinical Ultrafast Laser Surgery: Recent Advances and Future Directions. Journal of Selected Topics in

Quantum Electronics (2014); 20(2), 1-14.

• Ultrafast pulsed lasers can be used to achieve remarkable precision during surgical ablation. Through nonlinear

interactions with tissue, ultrafast lasers can provide a largely non-thermal mechanism of ablation and a unique ability to

create targeted damage within bulk tissue. These advantages have made ultrafast lasers the ideal surgical tool for various

novel applications in ophthalmology. Clinical adoption of ultrafast lasers in other surgical applications remains limited in part

due to the lack of a means for fiber delivery of ultrafast laser pulses as a flexible, hand-held surgical endoscope. This review

provides an overview of the recent advances in bringing this unique surgical tool into the clinic. We discuss fundamental

mechanisms and limitations of ultrafast laser ablation, novel techniques for overcoming these limitations, the current state of

clinical applications, and conclude with our recent efforts in developing fiber-coupled probes for flexible ultrafast laser

surgery and imaging.

​

​

6. Ferhanoglu O, Yildirim M, Subramanian K., Ben-Yakar A. A 5-mm Piezo-Actuated Fiber Probe for High Speed Ultrafast

Laser Microsurgery. Biomedical Optics Express (2014); 5(7), 2023-2036.

• The device consists of an air-core photonic bandgap fiber (PBF) for the delivery of high energy pulses, a piezoelectric tube

actuator for fiber scanning, and two aspheric lenses for focusing the light. Its inline optical architecture provides easy

alignment and substantial size reduction to 5 mm diameter as compared to our previous MEMS-scanning devices while

realizing improved intensity squared (two-photon) lateral and axial resolutions of 1.16 μm and 11.46 μm, respectively.

Our study also sheds light on the maximum pulse energies that can be delivered through the air-core PBF and identifies

cladding damage at the input facet of the fiber as the limiting factor. We have achieved a maximum energy delivery larger

than 700 nJ at 92% coupling efficiency. An in-depth analysis reveals how this value is greatly affected by possible slight

misalignments of the beam during coupling and the measured small beam pointing fluctuations. In the absence of these

imperfections, self-phase modulation becomes the limiting factor for the maximum energy delivery, setting the theoretical

upper bound to near 2 μJ for a 1-m long, 7-μm, air-core PBF. Finally, the use of a 300 kHz repetition rate fiber laser enabled

rapid ablation of 150 µm x 150 µm area within only 50 ms.

​

5. Yildirim M, Ferhanoglu O, Kobler J, Zeitels SM, Ben-Yakar A. Parameters Affecting Ultrafast Laser Microsurgery of

Subepithelial Voids for Scar Treatment in Vocal Folds. J Biomed Opt (2013); 18(11), 118001-1180014.

​

• Here, we present a comprehensive study of these parameters including ablation threshold and bubble lifetime in healthy

and scarred tissues. We also present a new method for extracting tissue-specific ablation threshold and scattering lengths

of different tissue layers. This method involves finding the ablation threshold at multiple depths and solving the equations

based on Beer’s law of light attenuation for each depth to estimate the unknown parameters. Measured threshold fluences

were 1.75  J/cm 2 for vocal folds and 0.5  J/cm 2 for cheek pouches for 3-ps, 776-nm laser pulses. Scarred pouches exhibited

30% lower threshold than healthy pouches, possibly due to the degraded mechanical properties of scarred collagen during

wound healing. The analysis of tissue architecture indicated a direct correlation between the ablation threshold and tissue

tensile strength and that the bubble lifetime is inversely related to tissue stiffness. Overall, this study sheds light on the

required laser parameters for successful implementation of ultrafast laser ablation for phonosurgery.

 

​

​

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4. Hoy CL, Everett WN, Yildirim M, Kobler J, Zeitels SM, Ben-Yakar A. Towards Endoscopic Ultrafast Laser Microsurgery

of Vocal Folds. J Biomed Opt (2012); 17(3), 038002-038008. 

​

• Vocal fold scarring is a predominant cause of voice disorders yet lacks a reliable treatment method. The injection of soft

biomaterials to improve mechanical compliance of the vocal folds has emerged as a promising treatment. Here, we study

the use of precise femtosecond laser microsurgery to ablate subsurface voids, with a goal of eventually creating a plane in

dense subepithelial scar tissue into which biomaterials can be injected for their improved localization. Specifically, we

demonstrate the ablation of small subepithelial voids in porcine vocal fold tissue up to 120 µm below the surface such that

larger voids in the active area of vocal fold mucosa ( ∼ 3×10  mm2) can eventually be ablated in about 3 min. We use sub-µJ,

776-nm pulses from a compact femtosecond fiber laser system operating at a 500-kHz repetition rate. The use of relatively

high repetition rates, with a small number of overlapping pulses, is critical to achieving ablation in a very short time while still

avoiding significant heat deposition. Additionally, we use the same laser for nonlinear optical imaging to provide visual

feedback of tissue structure and to confirm successful ablation. The ablation parameters, including pulse duration, pulse

energy, spot size, and scanning speed, are comparable to the specifications in our recently developed miniaturized

femtosecond laser surgery probes, illustrating the feasibility of developing an ultrafast laser surgical instrument.

 

​

​

3. Hoy CL, Ferhanoglu O, Yildirim M, Piyawattanametha W, Ra H, Solgaard O, Ben-Yakar A. Optical Design and Imaging

Performance Testing of a 9.6-mm Diameter Femtosecond Laser Microsurgery Probe. Optics Express (2011); 19(11),

10536-10552.

​

• We present the optical design of a 9.6-mm diameter fiber-coupled probe for combined femtosecond laser microsurgery

and nonlinear optical imaging. Towards enabling clinical use, we successfully reduced the dimensions of our earlier 18-mm

microsurgery probe by half, while improving optical performance. We use analytical and computational models to optimize

the miniaturized lens system for off-axis scanning aberrations. The optimization reveals that the optical system can be

aberration-corrected using simple aspheric relay lenses to achieve diffraction-limited imaging resolution over a large field of

view. Before moving forward with custom lenses, we have constructed the 9.6-mm probe using off-the-shelf spherical relay

lenses and a 0.55 NA aspheric objective lens. In addition to reducing the diameter by nearly 50% and the total volume by 5

times, we also demonstrate improved lateral and axial resolutions of 1.27 µm and 13.5 µm, respectively, compared to 1.64

µm and 16.4 µm in our previous work. Using this probe, we can successfully image various tissue samples, such as rat tail

tendon that required 2-3 × lower laser power than the current state-of-the-art. With further development, image-guided,

femtosecond laser microsurgical probes such as this one can enable physicians to achieve the highest level of surgical

precision anywhere inside the body.

 

​

​

 

​

2. Yildirim M, Dursunkaya Z, Okutucu T. An Interferometric Technique for Measuring Micron Level Clearances Filled

With a Lubricant. In STLE/ASME 2010 International Joint Tribology Conference (2010); pp. 167-169. American Society

of Mechanical Engineers.

​

• The aim of this study is to develop an interferometric technique to measure micron level clearances occurring in

small piston-cylinder arrangements; such as hermetically sealed compressors. A Cartesian model of the piston-cylinder

arrangement is manufactured and lateral and vertical motions are generated via a step motor, and micrometers,

respectively, to simulate the piston motion and the change of clearance during the motion. Experiments are conducted in

air and a lubricant. Measurements show the important effect of surface waviness of the mirror and the effect of the motion

of the carriage at micron level measurements

 

 

 

1. Yildirim M, Dursunkaya Z, Okutucu T. Experimental investigation of micron level clearances by fibre optic interferometry.

Proceedings of 11th International Conference on Tribology (2009); 296-300.

​

• In this study a fiber optic interferometer (FOI) was designed and constructed to measure micron level clearances

occurring in piston cylinder arrangements. A Cartesian model of the piston cylinder assembly is manufactured and lateral

motion and vertical displacement are generated via a step motor, and micrometers, respectively. Clearance measurements

were conducted in air and also in a lubricant. The range of vertical displacements is kept between 10-50 micrometers, and the

lateral motion is 13.5mm. The results show that the surface profile becomes dominant when vertical displacement values are

lower than 10 micrometers.

 

 

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23. Yildirim M. Three-photon imaging of intact human cerebral organoids to assess key components of early neurogenesis in Rett Syndrome. Picower                   

Institute’s Summer Retreat. Yarmouth, Boston, MA, June 3 2019.

​

22.  Yildirim M, Sugihara H, So PTC, Sur M. Imaging neuronal responses through cortical layers and subplate of visual cortex in awake mice with optimized            

three-photon microscopy. OSA BIOMED Conference, Tucson, AZ, 14-17 April 2019.

​

21. Yildirim M. Fly through the deep layers of the brain: High resolution imaging and stimulation of neurons. Webinar for Technology Development Foundation       

of Turkey. March 13 2019.

​

20. Yildirim M. Fly through the visual cortex: Advances in three-photon microscopy for neuroscience. Picower Institute’s Plastic Lunch. Boston, MA, March 6           

2019.

​

19. Yildirim M. Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy. Boston Turkish Biologists’            

Colloquium. Boston, MA, February 21 2019.

​

18. Yildirim M, Sugihara H, So PTC, Sur M. Imaging neuronal responses through cortical layers and subplate of visual cortex in awake mice with optimized      

three-photon microscopy. NESBO Conference, Boston, MA, 24 October 2018.

​

17. Yildirim M, Feldman D, Wang T, Ouzounov D, Chou S, Swaney J, Chung K, Xu C, So PTC, Sur M. Third harmonic generation imaging of intact human    

cerebral organoids to assess key components of early neurogenesis in Rett Syndrome. SPIE Photonics West Conference, San Francisco,

January 28-February 5 2017.

​

16. Gabay I, Subramanian K, Martin C, Yildirim M, Tuchin V, Ben-Yakar A. Increasing the penetration depth for ultrafast laser tissue ablation using glycerol  

based optical clearing. SPIE Photonics West Conference, San Francisco, California, 7-12 February 2016.

​

15. Yildirim M. Nonlinear Imaging Assisted Ulrafast Laser Surgery for the Treatment of Vocal Fold Scarring. Invited Talk at UT BME BOGO Seminar Series,  

Austin, Texas, 24 April 2015.

​

14. Yildirim M, Karajanagi S, Kobler J, Zeitels SM, Ben-Yakar A. Localization of biogel injection in scar tissue enabled by ultrafast laser ablation: model for

treatment of vocal fold scar. SPIE Photonics West Conference, San Francisco, California, 7-12 February 2015.

​

13. Yildirim M, Subramanian K, Ben-Yakar A. High speed deep tissue ablation with nonlinear imaging using an ultrafast fiber laser at 1045 nm. SPIE

Photonics West Conference, San Francisco, California, 7-12 February 2015.

​

12. Yildirim M, Ferhanoglu O, Kobler J, Zeitels SM, Ben-Yakar A. Parameters affecting ultrafast laser microsurgery for scar treatment in vocal folds. OSA        

BIOMED Conference, Miami, FL, 26-30 April 2014.

​

11. Yildirim M, Ferhanoglu O, Durr N, Ben-Yakar A. Maximum Imaging Depth Improvement with Third-Harmonic Generation Microscopy in Turbid Tissues.

OSA BIOMED Conference, Miami, FL, 26-30 April 2014.

​

10. Ferhanoglu O, Yildirim M, Subramanian K, Ben-Yakar A. A 5 mm piezo-actuated fiber device for high-speed ultrafast laser microsurgery. OSA BIOMED

Conference, Miami, FL,26-30 April 2014.

​

9.  Yildirim M, Ferhanoglu O, Subramanian K, Ben-Yakar A. A 5 mm diameter, piezo-scanning fiber device for high-speed ultrafast laser microsurgery. 40th  

NEBEC Conference, Boston, MA, 25-27 April 2014.

​

8.  Ferhanoglu O, Yildirim M, Ben-Yakar A. 5 mm piezo-actuated fiber endoscope for highspeed ultrafast laser microsurgery. SPIE Photonics West      

Conference, San Francisco, California, 1-6 February 2014.

​

7. Yildirim M, Ferhanoglu O, Kobler J, Zeitels SM, Ben-Yakar A. Maximum Imaging Depth Comparison of Second and Third Harmonic Generation

Microscopies in Porcine Vocal Folds. Invited Talk at the 8th Workshop on Advanced Multiphoton and Fluorescence Lifetime Imaging Techniques, Saarbrucken,

Germany, 1-3 July 2013.

​

6. Yildirim M, Ferhanoglu O, Kobler J, Zeitels SM, Ben-Yakar A. Study of Ultrafast Laser Microsurgery of Sub-Epithelial Voids for Scar Treatment in Vocal Folds.

SPIE Photonics West Conference, San Francisco, California, 2-7 February 2013.

​

5. Yildirim M, Hoy CL, Ferhanoglu O, Piyawattanametha W, Ra H, Solgaard O, BenYakar A. 9.6-mm Diameter Femtosecond Laser Microsurgery Probe. CLEO

Conference, San Jose, CA, 6-11 May 2012.

​

4. Hoy CL, Ferhanoglu O, Yildirim M, Piyawattanametha W, Ra H, Solgaard O, BenYakar A. 9.6-mm Diameter Femtosecond Laser Microsurgery Probe. OSA    

BIOMED Conference, Miami, FL, 28 April-2 May 2012.

​

3. Yildirim M, Ferhanoglu O, Kobler J, Zeitels SM, Ben-Yakar A. Ultrafast Laser Microsurgery, Simultaneous Multiphoton and SHG Imaging of Healthy and          

Scarred Vocal Folds. SPIE Photonics West, San Francisco, CA, 21-26 January 2012.

​

2. Yildirim M, Dursunkaya Z, Okutucu T. An Interferometric Technique for Measuring Micron Level Clearances Filled With a Lubricant. STLE/ASM International

Joint Tribology Conference, San Francisco, CA, 17-20 October 2010.

​

1. Yildirim M, Dursunkaya Z, Okutucu T. Experimental investigation of micron level clearances by fibre optic interferometry. International Conference on

Tribology, Belgrade, Serbia, May 13-15 2009.

​

Posters

​

12. Yildirim M, Delepine C, Feldman D, Pham V, Chou S, So PTC, Sur M. Three-photon imaging of intact human cerebral organoids to assess key components

of early neurogenesis in Rett Syndrome. Frontiers in Autism Research Scientific Retreat. Boston, MA, June 13 2019.

​

11. Yildirim M, Sugihara H, So PTC, Sur M. Imaging neuronal responses through all cortical layers and subplate of visual cortex in awake mice with optimized

three-photon microscopy.  SFN Conference, San Diego, November 3-7 2018.

​

10. Yildirim M, Delepine C, Feldman D, Pham V, Chou S, So PTC, Sur M. Three-photon imaging of intact human cerebral organoids to assess key

components of early neurogenesis in Rett Syndrome. Neurodevelopmental Disorders Symposium, Boston, MA, October 22 20189.

 

9.   Yildirim M, Delepine C, Feldman D, Wang T, Ouzounov D, Chou S, Swaney J, Chung K, Xu C, So PTC, Sur M. Three-photon imaging of intact human

cerebral organoids to assess key components of early neurogenesis in Rett Syndrome. SFN Conference, Washington, DC, November 11-15 2017.

​

8.   Yildirim M, Feldman D, Wang T, Ouzounov D, Chou S, Swaney J, Chung K, Xu C, So PTC, Sur M. Third harmonic generation imaging of intact human

cerebral organoids to assess key components of early neurogenesis in Rett Syndrome. SFN Conference, San Diego, November 12- 16 2016.

​

7.    Yildirim M, Ferhanoglu O, Durr N, Ben-Yakar A. Maximum Imaging Depth Improvement with Third-Harmonic Generation Microscopy in Turbid Tissues.

Gordon Research Conference on Lasers in Biology and Medicine, Boston, MA, 13-18 July 2014.

​

6.    Ferhanoglu O, Yildirim M, Subramanian K, Ben-Yakar A. A 5 mm piezo-scanning fiber device for high-speed ultrafast laser microsurgery. Gordon

Research Conference on Lasers in Biology and Medicine, Boston, MA, 13-18 July 2014.

​

5.    Yildirim M, Ferhanoglu O, Durr N, Ben-Yakar A. Maximum Imaging Depth Improvement with Third-Harmonic Generation Microscopy in Turbid Tissues.  

40th NEBEC Conference, Boston, MA, 25-27 April 2014.

​

4.    Yildirim M, Ferhanoglu O, Kobler J, Zeitels SM, Ben-Yakar A. Maximum Imaging Depth in Third Harmonic Generation using 1552 nm. SPIE Photonics  

West Conference, San Francisco, California, 2-7 February 2013.

​

3.     Ferhanoglu O, Yildirim M, Ben-Yakar A. Ultrafast Laser Scalpel: A Piezo Scanned Fiber Probe for Tissue Ablation. SPIE Photonics West Conference,  

San Francisco, California, 2-7 February 2013.

​

2.     Yildirim M, Ferhanoglu O, Kobler J, Zeitels SM, Ben-Yakar A. Ultrafast Laser Surgery and Nonlinear Optical Imaging of Healthy and Scarred Vocal    

Folds. Gordon Conference: Lasers in Medicine and Biology, Boston, Massachusetts, 22-27 July 2012.

​

1.     Hoy CL, Ferhanoglu O, Yildirim M, Eversole D, King D, Ben-Yakar A. 9.6 mm Diameter Femtosecond Laser Scanning Probe for Imaging and Plasmonic  

Nanosurgery. Gordon Conference: Lasers in Medicine and Biology, Boston, Massachusetts, 22-27 July 2012.

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Link